Artists like Secreto "El Famoso Biberon"

Manuel Varet Marte, known as Vakero, is a Dominican singer and rapper, believed to be one of the most important acts of the Dominican urban music movement and one of the first to gain international exposure. Known for blending elements of punta, cumbia and merengue with Dominican urban and dembow music, he is heavily influenced by reggae and afro-pop with his characteristic style influenced by the rastafari movement.

Yameiry Josefina Infante Honoret, known in show business as La Materialista, is a Dominican singer, rapper, actress and vedette.

R.K.M & Ken-Y is a Puerto Rican reggaeton duo formed in 2003 by José Nieves (R.K.M) and Kenny Vázquez (Ken-Y). The artists are renowned in the Latin music world for being the first to successfully fuse mainstream pop music with the reggaeton street rhythms of Puerto Rico and expose the style to a wide international audience. The sound introduced by R.K.M & Ken-Y would go on to inspire the pop reggaeton songs of successful acts such as CNCO, J Balvin, and Maluma. The duo had a very successful career with the Spanish-speaking audience of Latin America, the United States, and Spain until their separation in 2013. In June 2017, the duo announced their official return by Pina Records. In mid-2021 the Duo confirmed that they are on hiatus and are currently working on their solo projects.

David Luciano Acosta, known professionally as Baby Ranks, is a Puerto Rican and Dominican reggaeton artist. He has co-billing on the Luny Tunes album Mas Flow 2, and sings on multiple tracks including the single "Mayor Que Yo". The album ranked #5 on the Billboard year-end Latin Album Chart, #7 on the year-end Tropical Album Chart, and #9 on the Reggae Album Chart, for the year 2005. "Mayor Que Yo" won Reggaeton Song of the Year at the 2006 Latin Billboard Music Awards.