Artists like Big Mama Thornton

Elmore James was an American blues guitarist, singer, songwriter, and bandleader. Noted for his use of loud amplification and his stirring voice, James was inducted into the Rock and Roll Hall of Fame in 1992. His slide guitar technique earned him the nickname "King of the Slide Guitar".

J. B. Lenoir was an American blues guitarist and singer-songwriter, active in the Chicago blues scene in the 1950s and 1960s. In The Encyclopedia of Popular Music he is described as both an "extrovert R&B man in the leopard-skin jacket who chanted infectious trifles" and a "thoughtful and intelligent writer of starkly honest blues songs."

Huddie William Ledbetter, better known by the stage name Lead Belly, was an American folk and blues singer notable for his strong vocals, virtuosity on the twelve-string guitar, and the folk standards he introduced, including his renditions of "In the Pines", "Pick a Bale of Cotton", "Goodnight, Irene", "Black Betty", "Midnight Special", "Cotton Fields", and "Boll Weevil".

Fred McDowell, known by his stage name Mississippi Fred McDowell, was an American singer-songwriter and guitarist of hill country blues music.

Robert Calvin Bland, known professionally as Bobby "Blue" Bland, was an American blues singer. Bland developed a sound that mixed gospel with the blues and R&B. He was described as "among the great storytellers of blues and soul music... [who] created tempestuous arias of love, betrayal and resignation, set against roiling, dramatic orchestrations, and left the listener drained but awed." The inspiration behind his unique style was a Detroit Preacher, CL Franklin, because Bland studied his sermons. He was sometimes referred to as the "Lion of the Blues" and as the "Sinatra of the Blues". His music was influenced by Nat King Cole.

Odetta Holmes, known mononymously as Odetta, was an American singer, songwriter, and actress. Referred to as "The Voice of the Civil Rights Movement", her musical repertoire consisted largely of American folk music, blues, jazz, and spirituals.

Nehemiah Curtis "Skip" James was an American Delta blues singer, guitarist, pianist and songwriter. AllMusic stated: "Coupling an oddball guitar tuning set against eerie, falsetto vocals, James' early recordings could make the hair stand up on the back of your neck."